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Cadence Taps NVIDIA Blackwell to Accelerate AI-Driven Engineering Design and Scientific Simulation




Cadence Taps NVIDIA Blackwell to Accelerate AI-Driven Engineering Design and Scientific Simulation


A new supercomputer offered by Cadence is poised to support a suite of engineering design and life sciences applications accelerated by NVIDIA Blackwell systems and NVIDIA CUDA-X software libraries. The collaboration between Cadence and NVIDIA promises to drive innovation across industries, from autonomous machines to pharmaceutical research.


With the integration of NVIDIA Blackwell systems and CUDA-X software libraries, the Millennium M2000 Supercomputer offers significant performance gains for complex engineering design tasks, enabling faster silicon, systems, and drug development.


  • Cadence and NVIDIA have partnered to accelerate engineering design and scientific simulation with the development of the Cadence Millennium M2000 Supercomputer.
  • The supercomputer leverages NVIDIA Blackwell systems and CUDA-X software libraries to accelerate a suite of engineering design and life sciences applications.
  • The partnership aims to drive innovation across industries, including autonomous machines, pharmaceutical research, and data centers.
  • Cadence has integrated various NVIDIA technologies, such as BioNeMo NIM microservices and Llama Nemotron reasoning models, into its Orion molecular design platform and JedAI Platform.
  • The collaboration promises to tackle complex engineering design challenges with AI-powered supercomputers like the Millennium M2000 Supercomputer.



  • Cadence, a leading provider of technology for electronic design automation, has announced its latest partnership with NVIDIA, a pioneer in artificial intelligence (AI) computing. This collaboration marks a significant milestone in the development of the Cadence Millennium M2000 Supercomputer, a cutting-edge supercomputer that leverages NVIDIA Blackwell systems and NVIDIA CUDA-X software libraries to accelerate a suite of engineering design and life sciences applications.

    The Millennium M2000 Supercomputer is poised to support a range of high-performance computing (HPC) workloads, including electronic design automation, system design, and life sciences. This powerhouse of computational capability is made possible by the integration of NVIDIA HGX B200 systems and NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs. With this combined hardware and software ecosystem, engineers can run massive simulations to drive breakthroughs in the design and development of autonomous machines, drug molecules, semiconductors, data centers, and more.

    At the heart of this collaboration is a deep understanding of the need for accelerated computing solutions that can tackle complex engineering design challenges. Anirudh Devgan, president and CEO of Cadence, acknowledged years of effort in developing this partnership, noting that it was a combination of advancements on the hardware and system side by NVIDIA – as well as rewriting software to take advantage of that technology.

    In a key conversation during CadenceLIVE, where the announcement was made, Jensen Huang, founder and CEO of NVIDIA, emphasized the importance of AI factories in revolutionizing every aspect of industry. "The work we're doing together recognizes that there's a whole new type of factory that's necessary," he said. "AI is going to infuse into every single aspect of everything we do. Every company will be run better because of AI, or they'll build better products because of AI."

    This vision of the future, where AI is integral to all aspects of business and industry, is reflected in the development of the Cadence Millennium M2000 Supercomputer. With optimized hardware and AI software from NVIDIA, engineers and researchers can create more complex, detailed simulations that deliver accurate insights for faster silicon, systems, and drug development.

    Cadence has leveraged accelerated computing solutions to tackle specific challenges across diverse industries. For example, simulating thermal dynamics for chip design, fluid dynamics for aerospace applications, and molecular dynamics for pharmaceutical research – all of these complex tasks have seen significant performance gains thanks to the integration of NVIDIA Blackwell and CUDA-X software libraries.

    NVIDIA engineering teams supported design verification and chip bring-up workflows by utilizing Cadence Palladium emulation platforms and Protium prototyping platforms. Meanwhile, Cadence utilized NVIDIA Grace Blackwell-accelerated systems to calculate fluid dynamics at work in aircraft takeoff and landing simulations – a task that previously took several days to complete on a CPU cluster with hundreds of thousands of cores.

    Cadence has also integrated NVIDIA BioNeMo NIM microservices into its Orion molecular design platform, as well as NVIDIA Llama Nemotron reasoning models into the Cadence JedAI Platform. Moreover, the company has adopted the NVIDIA Omniverse Blueprint for AI factory digital twins, connected to the Cadence Reality Digital Twin Platform.

    The blueprint enables engineering teams to test and optimize power, cooling, and networking in an AI factory with physically based simulations – all before construction starts in the real world. This capability allows engineers to make faster configuration decisions and future-proof the next generation of AI factories.

    This collaboration marks a significant milestone in the partnership between Cadence and NVIDIA, pushing the boundaries of what is possible in AI-driven engineering design and scientific simulation. With the integration of NVIDIA Blackwell systems and CUDA-X software libraries, the Millennium M2000 Supercomputer promises to drive innovation across industries – from autonomous machines to pharmaceutical research.

    As technology continues to advance at breakneck speed, it becomes clear that the future of industry will be shaped by AI-powered supercomputers like the Cadence Millennium M2000. The implications of this collaboration are far-reaching, offering insights into a future where AI is integral to every aspect of business and industry.

    In conclusion, the partnership between Cadence and NVIDIA has given rise to the Cadence Millennium M2000 Supercomputer – a powerhouse of computational capability that promises to drive innovation across industries. With its optimized hardware and AI software, this supercomputer is poised to tackle some of the most complex engineering design challenges in existence.

    Summary:

    Cadence, a leading provider of electronic design automation technology, has partnered with NVIDIA to accelerate engineering design and scientific simulation through the development of the Cadence Millennium M2000 Supercomputer. This collaboration marks a significant milestone in leveraging AI-powered solutions for accelerated computing, promising to drive innovation across industries from autonomous machines to pharmaceutical research.



    Related Information:
  • https://www.digitaleventhorizon.com/articles/Cadence-Taps-NVIDIA-Blackwell-to-Accelerate-AI-Driven-Engineering-Design-and-Scientific-Simulation-deh.shtml

  • https://blogs.nvidia.com/blog/cadence-millennium-nvidia-blackwell/


  • Published: Wed May 7 16:53:24 2025 by llama3.2 3B Q4_K_M











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